2 Current advances in integrating gene editing with immunotherapy for HIV. For R5-tropic HIV-1 strains—which dominate during the early and chronic phases of infection—C-C chemokine receptor 5 (CCR5) ...

CCR5-tropic virus is the predominant virus encountered, though CXCR4-tropic virus strains are more likely encountered, in patients with advanced HIV disease. Results from Phase III clinical trials ...

Peptide ligands presented by human leukocyte antigen (HLA) molecules on the cell surface represent the immunopeptidome that could be utilized for identification of antigenic peptides for immunotherapy ...