Despite challenges in studying allergen-specific CD4+ T cells in food allergy, targeted approaches signal progress while emerging prospects show future promise.

Study: Measuring anti-islet autoimmunity in mice and human by profiling peripheral blood antigen-specific CD4 T cells. Image Credit: Peackstock / Shutterstock.com About the study Blood samples ...

These soluble protein agonists can replicate Notch activation in suspension culture, opening the door to scalable T-cell therapies.

After the exclusion of patients with genetic and acquired causes of CD4 lymphopenia, the study population included 91 patients with ICL during 374 person-years of follow-up. The median CD4+ T-cell ...