Thymically committed regulatory CD4 T cells (tTregs ... Experimental approaches mapping the cell fate in in-vitro cultures may help clarify the origin and the cell differentiation trajectories. Our ...

RNA modification related enzymes exhibit distinct functions across various tissues and cells in autoimmune diseases. RNA modification related enzymes play a crucial role in the differentiation of CD4 ...

Adding the TCRA or TCRB 3' UTR to an anti-CD19 chimeric antigen receptor (CAR) improves the ability of the corresponding CAR-T cells to kill tumor cells in vitro. Here, we identified mRNAs that ...

The data analysis is rigorous and the experiments performed are appropriate. The findings of the manuscript will expand upon previous findings of a role for histone deacetylase 3 in thymocyte ...