This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to order RNA sequences online and have them shipped by FedEx. In a short while ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

CRISPR epigenome editing successfully reactivates silenced genes in Prader-Willi Syndrome, highlighting potential for ...

For its fourth quarter of 2024, CRISPR booked revenue of just under $36 million. On the bottom line, CRISPR flipped to a generally accepted accounting principles (GAAP) loss of $37 million ($0.44 ...

June 20, 2024 — Research scientists found that a 'one-two punch' of combining the immunosuppressive drug ruxolitinib with existing checkpoint inhibitor therapies may be a more effective way to ...

Borussia Dortmund and Paris Saint-Germain both hold three-goal advantages while PSV Eindhoven face a first-leg deficit and the stage is set for another thriller between Real Madrid and Manchester ...