Hosted on MSN10h
CRISPR Unlocks ‘Sleeping’ Genes—A Potential Cure for Prader-Willi Syndrome?
CRISPR epigenome editing successfully reactivates silenced genes in Prader-Willi Syndrome, highlighting potential for ...
Harvard Medical School11h
Creating the World’s First CRISPR Medicine, for Sickle Cell Disease
In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...
AZoLifeSciences on MSN20h
Using CRISPR-Cas9 Gene Editing for Chromosomal Rescue in Down Syndrome
Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...
FierceBiotech1d
It's curtain close for Spotlight: Gene editing biotech shutters
CRISPR-based Spotlight Therapeutics has shut down, former CEO Mary Haak-Frendscho, Ph.D., confirmed with Fierce Biotech. | ...
eLife1d
Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish
This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...
CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...