Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
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Hosted on MSNCRISPR-Cas9 Off-Target Effects: Challenges and SolutionsThe CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
Scientists at the Garvan Institute of Medical Research have discovered that certain gene variations associated with leukemia ...
Researchers at Oregon Health & Science University have developed the first transgenic nonhuman primate model—genetically ...
Ongoing launch of CASGEVY ® continues to gain momentum; new cell patient collection initiations expected to significantly grow in 2025- -More than 50 authorized treatment centers (ATCs) activated ...
Crispr Therapeutics AG has revenue declines but holds strong financials. Promising Sickle Cell therapy & 2025 data readouts ...
In response to infection, immune cells stream into tissues to fight ... "We are expanding our CRISPR pooled spatial screening to profile the impacts of many types of genetic perturbations at ...
CRISPR is an example of gene editing that ... that only 7 of the studies reported on the levels of tumor-specific immune response. A 2023 review noted that there are hundreds of clinical trials ...
Researchers sought to determine whether the CAR-T therapy volamcabtagene durzigedleucel (CTX130) would be effective in patients with T-cell lymphoma.
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