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Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...
Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...
"In both diseases, cells suffer from toxic protein buildup. It appears there is a common mechanism that gets rid of these proteins to prevent them from clustering. NU-9 is rescuing the pathway ...
Department of Materials Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana−Champaign, Urbana, Illinois 61801, United States ...
coli cells infected with bacteriophage Goslar, with both the phage nuclei and EPI vesicles fluorescently labeled. The viral DNA is inside ... “A few years ago we discovered the phage nucleus that ...
Each new cell’s nucleus contains one full copy of the somatic genome ... of kinetochore proteins on eliminated DNA in Mesorhabditis. 2 Using a fluorescent label, she visualized DNA fragments as tiny ...
The bottom left image is for the cell nucleus (labeled by Hoechst 33342, 2 μg/ml). The bottom middle image is an overlay of SDot-Tat and B23 protein. The bottom right image is an overlay of SDot, B23 ...
Destabilization of a non-enveloped virus generates a membrane transport-competent viral particle. Here we probe polyomavirus SV40 endoplasmic reticulum (ER)-to-cytosol membrane transport, a decisive ...