Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.

Supported [in part] by a Medical Research Future Fund Stem Cell Therapies Mission grant (APP2016039), National Health and Medical Research Council of Australia grant (APP2008300, APP2017898, ...

On Crowncast, Enrico Pesenti explains how cancer drug resistance forms and how advanced technologies are helping researchers ...

Preclinical studies have demonstrated IDE275's (GSK959) potential as a best-in-class WRN inhibitor, inducing single-agent tumor regressions in MSI-H patient-derived xenograft (PDX) and cell line ...

This study is led by Prof. Kenneth To (School of Pharmacy, The Chinese University of Hong Kong) and Dr. William Cho ...

LaunXP receives exclusive development and commercialization rights for vebreltinib in combination with an EGFR inhibitor in Asia (excluding mainland China, Hong Kong and Macau) for the treatment of ...

In fact, one recent study reported that TCM-derived compounds like quercetin ... by inhibiting the growth of clear cell renal carcinoma (ccRC) xenograft tumors in a dose-dependent manner.

Esophageal squamous cell carcinoma (ESCC ... In vivo experiments using patient-derived xenograft (PDX) models in immunodeficient mice demonstrated that dronedarone treatment significantly reduced ...

The theory was that it could get into the skin and affect estrogen receptors in breast cells. Type “aluminum ... vivo mouse studies with patient-derived xenografts [tissue taken from a patient ...