During this transformation, one centriole forms de novo initially, and a second centriole assembles shortly thereafter (Dingle and Fulton, 1966; Fritz-Laylin et al, 2016; Fulton and Dingle, 1967, 1971 ...

This unique approach, which combines the very high resolution of expansion microscopy and kinematic reconstruction, has enabled us to model the first 4D assembly of the human centriole.

This work, published in the journal Cell, elucidates the complexities of centriole assembly. It also opens up many new avenues for the study of other cell organelles.

Time-series reconstruction of the molecular architecture of human centriole assembly. Cell, 2024; DOI: 10.1016/j.cell.2024.03.025 ...

Researchers at IRB Barcelona's Microtubule Organization lab, headed by Dr. Jens Lüders, have identified a new crucial role for γTuRC as a centriole stabilizer and have also identified a form of ...

News Release 1-Nov-2021 Centriole instability might contribute to some cases of microcephaly Peer-Reviewed Publication Institute for Research in Biomedicine (IRB Barcelona) ...

Researchers at IRB Barcelona's Microtubule Organization lab, headed by Dr. Jens Lüders, have identified a new crucial role for γTuRC as a centriole stabilizer and have also identified a form of ...

Newly discovered sperm movement could help diagnose, treat male infertility Centriole's role in sperm evolved from a shock absorber to a transmission system Date: June 28, 2021 Source: University ...

The centriole's intricate architecture underlies its crucial role in assembly of centrosomes and cilia/flagellae. Here, in situ and ex vivo cryo‐electron tomography of centrioles from Chlamydomonas, ...

By expressing animal centriole components in fission yeast, we observed that the SPB recruits them. We further demonstrate that the SPB conserved PCM component Pcp1/pericentrin recruits the centriole ...

Each centriole was assigned to a specific Quartile (Q) depending on their relative position to the anterior-posterior axis of the cell that crosses the cell centroid (Taniguchi et al., 2011). If the ...

In all species in which centrioles have been defined, centrioles are comprised of microtubules arranged in a 9-fold symmetrical cylinder. During centriole duplication in S phase, a 9-fold symmetric ...