Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Bioinformaticians have established that the genes in bacterial genomes are arranged in a meaningful order. They describe that the genes are arranged by function: If they become increasingly important ...

This mechanism ensures that genetic material is properly shuffled between chromosomes, preventing errors that could lead to disorders such as miscarriages, infertility, birth defects, and even cancer.

A new AI system, dubbed InstaNovo, could revolutionise protein sequencing just as AlphaFold transformed protein structure prediction, its developers claim. While DNA sequencing is routine, determining ...

Large networks of tryptophan form in microtubules, amyloid fibrils, transmembrane receptors, viral capsids, cilia, centrioles, neurons, and other cellular complexes. The QBL's confirmation of ...

Chromosomes are the carrier of our genomic information and hold vital clues of the evaluation and therapeutic outcome of breast cancer. “In an innovative approach, our study explores how VPA ...

State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, China; Center for Translational Medicine, The First ...

View Full Profile. Learn about our Editorial Policies. Earlier methods to synthesize HAC relied on linking shorter DNA constructs into a larger chromosome within the cell in a process called ...

When Nettie Steven discovered the Y chromosome in 1905 while studying the mealworm Tenebrio molitor, she identified it as a sex-determining chromosome. As it turns out, the chromosome also has ...

The embryo development and pregnancy outcomes were analyzed in different groups. Conclusion: Male with chromosome polymorphism (CPM) have a lower blastocyst rate and a higher aneuploidy rate than ...