These dangerous drugs are created by changing the molecular structure of an existing drug ... when combined with other CNS depressants like alcohol, sedatives or tranquilizers.

A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse model, preventing lung pathology and reducing brain dysfunction. The study provides proof-of-principle ...

Scientists have long considered ketones (a fundamental chemical ... of drug molecules. Yet both share a critical limitation: ...

Although structure-based drug discovery is still in its infancy for antibacterial-drug discovery, the growing number of molecular targets for which structural information is available makes this ...