High-potency Class I to II topicals are frequently used first line to suppress inflammation and symptoms of itching. These agents are often useful as therapy for stage IA disease, but are often ...

Skin biopsy specimens of three lesions on her back were consistent with cutaneous T-cell lymphoma (CTCL). On physical examination, she had erythematous patches and plaques with ill-defined borders ...

and potentially cutaneous T-cell lymphoma. All of these diseases have macrophage components and may show a beneficial response to local cutaneous therapy with immunotoxins such as these.