Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

Accurately counting viable cells in a sample is crucial for various biological assays, including normalization and assessing drug impacts on cell proliferation for cancer research. Regular cell ...

IgA nephropathy (IgAN) is characterized by the deposition of IgA1-containing immune complexes in the glomerular mesangium. The pathogenesis follows a 4-hit cascade: ...

Biocartis announced the launch of its real-time quantitative polymerase chain reaction assay to detect POLE and POLD1 mutations in endometrial cancer. Biocartis has launched a fully automated, ...

Different approaches are used for PD-L1 IHC. We analyzed paired PD-L1 IHC data on urothelial cancer samples using the SP142 and 22C3 assays from the phase III IMvigor130 trial and found discordant ...

One of the most familiar and widely used methods for quantifying cell proliferation is the measurement of tritiated ... N.J., offers both a [14C]-thymidine and a [3H]-thymidine uptake assay system, ...

“We have a long-standing legal obligation as a state party to the nuclear Non-Proliferation Treaty (NPT) never to develop or acquire nuclear so it would mean a withdrawal from that treaty if we were ...

The names of the investors were not disclosed. The Vancouver, Canada-based cancer testing firm said that it would use the funds to support the commercial launch of its lung cancer assay. This ...

The research shows that novel cancer drugs designed to inhibit CDK7 can, within minutes, shut down gene expression pathways that drive cell proliferation in dozens of different kinds of tissues.