A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

Lying as the central hub in the membrane trafficking, the Golgi apparatus plays a pivotal role in intracellular secretory pathway by modifying newly synthesized proteins and lipids, packaging ...

For instance, in the Golgi apparatus, which processes and sorts proteins, vesicles move rapidly over distances of just a few hundred nanometers.

Post-Golgi vesicles transport GBR/Syt11 complexes to pre- and postsynaptic sites Syt11-interacting proteins also included the kinesin-3 motor KIF1A (Fig. 1A), which mediates transport of various ...

When vesicles bud off from the trans-Golgi and fuse with endosomes, lysosomes are formed. In contrast, the ER is where the lysosomal hydrolases are synthesized.

Here, we report that STING-induced noncanonical autophagy depends on an unexpected ion channel function of STING. Ligand-bound STING forms an electron-sparse pore in its transmembrane domain that ...

The Golgi apparatus is a significant membrane-bound organelle of eukaryotic cells that is made up of a series of flattened, stacked pouches (called cisternae). The Golgi apparatus packages proteins ...

Could some vesicles come from neurons? Ralph Nixon of New York University told Alzforum that the components are consistent with PANTHOS, aka perinuclear rosettes of Aβ fibrils mixed with ER, Golgi, ...

The protein stops periodically to emerge from one vesicle, be further modified, then request and catch another newly assembled vesicle -- the previous ride moves into the Golgi -- then move on in ...