Hyperacute rejection most commonly occurs while the patient is still in the operating room; the kidney frequently turns black before the surgical team's eyes. Antibody-to-transplant antigens can ...

In mid-2024, the patient underwent a kidney transplant. Though he was relatively young for a transplant, that’s not where he ...

Cyclosporine, generally introduced in the 1980s, was a breakthrough in preventing rejection and opened a new era in transplant surgery. In 1986 alone, for example, nearly 9,000 kidney transplants ...

Recent advances using transgenic animals or exogenous complement inhibitors have demonstrated prevention of hyperacute ... the transplantation of rat kidneys and hearts and indicates that ...

The recipient was Tim Andrews, a 66-year-old New Hampshire resident who had end-stage kidney disease and was on dialysis for ...

The first clinical trials using organs from genetically modified pigs offer hope to patients with kidney failure, who face a ...

"As of April 7, the transplanted kidney has been working ... genes to the pig used in the transplant and remove three pig genes that can cause hyperacute rejection, the university said.

Thirty years ago, I spoke at a conference on xenotransplantation — the transplantation ... attached a kidney from a pig that had been genetically engineered to avoid immunologic rejection ...

If an ABO-incompatible graft is transplanted, hyperacute rejection will occur (the possible exception being a liver graft). In kidney transplantation, preformed circulating cytotoxic antibodies in ...