T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy ...

Previous work by the team had shown that the NOTCH signaling pathway played a central role in differentiation, which is essential for an effective immune response by CD8 + T cells. In the new ...

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

Brain tissue analysis of an animal model has revealed the potential role of immune system dysfunction in the onset and ...

and the large group of white blood cells which orchestrate the immune defense. This process, known as differentiation, must be precisely regulated to ensure a balanced production of mature blood cells ...

The immune system works to maintain homeostasis throughout the body. Various cell types and immune mechanisms work in concert to fight disease. Specifically, two waves of immunity orchestrate a robust ...

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

Immune checkpoint inhibitors ... transcriptomic analyses further showed that combination therapy targeting DDX54 promoted the differentiation of T cells and memory T cells that suppress tumors, while ...

Immune checkpoint inhibitors ... showed that combination therapy targeting DDX54 promoted the differentiation of T cells and memory T cells that suppress tumors, while reducing the infiltration ...