Similar changes likely affect kidney cell gene expression, potentially modifying protein production essential for normal filtration and transport functions. Nephron loss acceleration represents ...

A research team led by Kyoto University said Wednesday it has prevented kidney functions from declining in mice using human ...

Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number ... mechanisms by which these genes function in both normal and abnormal kidney development.

Kyoto, April 23 (Jiji Press)--A research team led by Kyoto University said Wednesday it has successfully prevented kidney functions from ... fold proliferation of nephron progenitor cells derived ...

Using a mouse model of AKI, the research team first demonstrated the therapeutic potential of human iPS cell-derived nephron progenitor ... the deterioration of kidney function.

and the analysis of the consequences of kidney-specific gene knockouts on the distal nephron function. The acquired knowledge in these areas has allowed us to make a picture of the complex coordinated ...

Another case involved a patient with a solitary kidney and chronic renal insufficiency, which raised considerations about potential nephron loss if nephroureterectomy were performed. The discussion ...