The lightsheet system is perfect for capturing 3D fluorescent images of organisms, tissue explants, and cell cultures over long periods. Basically, it shines a thin sheet of laser light on a slice of ...

LightSheet microscopy is a fluorescence technique that projects a thin ‘sheet’ of excitation light perpendicular to the direction of observation. This type of a system uses cylindrical optics to focus ...

This microscope provides fast and gentle imaging of living ... detectors enable observations of the fastest processes at the lowest illumination light levels. The light sheet geometry illuminates only ...

Light-sheet fluorescence microscopy has become the leading method for imaging large, tissue-cleared samples in 3D, owing to its optical sectioning, reduced photodamage, and rapid acquisition.

Light microscopy is one of the most essential technologies in life science research. Advances in optoelectronic detectors and ...

Soon, he picked up a side project: developing one of the first confocal fluorescent microscopes. Stelzer and his colleagues designed a device with a pinhole that filtered out-of-focus layers of laser ...

whether tissue clearing reagent can be used to clear spheroids expressing fluorescent proteins and we learn more about the new 3D Clear Tissue Clearing reagent from Corning Life Sciences. Scientists ...

If you're using a 2D technique, you might be. With a light sheet microscope, you can explore the full 3D complexity of your intact samples, from micrometers to centimeters, at single-cell resolution.