While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

These advances have made it possible for scientists to create pigs with organs that are more compatible with human biology, thus reducing the chances of rejection. One common edit, for instance, ...

In 2023, a modified pig liver was externally connected to a human subject for 72 hours. Likewise, genetically modified porcine kidneys have previously been transplanted into brain-dead patients ...

U.S. researchers are about to test if livers from gene-edited pigs could treat people with sudden liver failure — not with a ...

Doctors in China have become the first to report details about a transplant of a genetically modified pig liver into a human. The liver was transplanted last year into a person who was brain-dead ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...