Spinal muscle atrophy is a genetic disorder. Most forms of SMA are caused by mutations of the survival motor neuron 1 gene (SMN1) on the fifth chromosome, resulting in insufficient expression levels ...

We validated previous observations of neuronal cell number changes and muscle fiber distribution. We found that the increase in neuron cell number tends to lag behind the rapid expansion of somatic ...

The findings were presented at the Muscular Dystrophy Association‘s 2025 MDA Clinical & Scientific Conference, held March 16-19, in the talk, “Restoration of motor neuron function ... also led to more ...

Introduction Patients with ventilator-dependent motor neuron disease (MND) may request withdrawal of their assisted ventilation. Facilitating this process as a healthcare professional (HCP) can be ...