The drug Blujepa, from drugmaker GSK, provides a new treatment option as bacteria increasingly become resistant to the ...

Gepotidacin is the first new class of oral antibiotics for uUTIs in nearly 30 years, addressing rising drug resistance. Phase 3 trials showed gepotidacin's non-inferiority to nitrofurantoin ...

Blujepa (gepotidacin) is the first new antibiotic class approved in nearly 30 years ... In these studies, Blujepa was compared with nitrofurantoin, a leading treatment for uncomplicated UTIs.

Blujepa sets itself apart from nitrofurantoin as ... To put it simply, the drug is designed to specifically inhibit bacterial DNA in the E. coli class, which causes the majority of UTI infections ...

In the EAGLE-3 experiment, gepotidacin was statistically superior to nitrofurantoin. “As a first-in-class investigational oral antibiotic with activity against common uropathogens, including ...

The US Food and Drug Administration has approved a new type of antibiotic to treat urinary tract infections. The pill, gepotidacin, will be sold under the brand name Blujepa and is expected to be ...

FDA approval of Blujepa is based on the results of two Phase 3 studies that showed the therapeutic benefit from the GSK drug was not inferior to treatment with nitrofurantoin, an old antibiotic ...

""We are proud to have developed Blujepa, the first in a new class of oral antibiotics ... as well as or better than nitrofurantoin, the frontline antibiotic which is currently used to treat ...

Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial ... to receive gepotidacin 1500mg twice daily or nitrofurantoin 100mg twice daily for 5 days.

Gepotidacin is an oral, first-in-class triazaacenaphthylene antibiotic that inhibits bacterial DNA replication by blocking 2 different type II topoisomerase enzymes.

47% in patients treated with nitrofurantoin ... the first in a new class of oral antibiotics for uUTIs in nearly three decades, and to bring another option to patients given recurrent infections ...