continue along the nephron tubule as urine. This eventually passes down to the bladder. In carrying out these processes, the kidney is able to fulfil its functions of regulating the water and ion ...

Renal hypoplasia, defined as abnormally small kidneys with normal morphology and reduced nephron number ... mechanisms by which these genes function in both normal and abnormal kidney development.

ClC-K2 is expressed more broadly in the distal nephron; expression levels are ... results in a 'double knockout' of the functions of both ClCKA and ClCKB, manifesting as Bartter syndrome type ...