This study is led by Prof. Kenneth To (School of Pharmacy, The Chinese University of Hong Kong) and Dr. William Cho ...

The poster presented data from AUTX-703, a potent, selective and orally bioavailable heterobifunctional degrader of KAT2A/B, an AURIGIN-identified histone acetyltransferase driving small cell lung ...

NEWTON, Mass., April 03, 2025 (GLOBE NEWSWIRE) -- Auron Therapeutics, a clinical-stage biotechnology company targeting cell-state plasticity to improve patient outcomes in oncology and ...

1Cell and Tumor Biology, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.

Preclinical studies have demonstrated IDE275's (GSK959) potential as a best-in-class WRN inhibitor, inducing single-agent tumor regressions in MSI-H patient-derived xenograft (PDX) and cell line ...

ZW171, a mesothelin (MSLN)-targeting T cell engager, currently in global Phase 1 clinical studies, shows promising preclinical activity in an expanded range of MSLN-positive tumor models including ...

You are able to gift 5 more articles this month. Anyone can access the link you share with no account required. Learn more. BIDDEFORD — It is not unusual to see kids blowing bubbles, running ...

Researchers have uncovered a promising therapeutic target for adenoid cystic carcinoma (ACC), a rare cancer of the salivary glands with few treatment options. The study, "PRMT5 inhibition has a ...

While a previous study introduced IL-15 and CCL19 into CAR-T cells and evaluated the anti-tumor effects using a zebrafish xenotransplantation model (42), mouse xenograft models remain the gold ...

Tumor-derived exosomes (TEXs ... Similarly, exosomal proteins derived from the serum of patients with advanced malignancies have been shown to increase the expression of vimentin (VIM) and enhance the ...