More than 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study, ...

Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study. By creating the most complete and detailed genetic 'map' of kidney function to ...

Sep. 18, 2024 — A team developed a human iPS cell-derived kidney organoid-based proximal tubule-on-chip -- OPTECs-on-Chip -- that mimics in vivo renal physiology more closely than ever before.

CAMBRIDGE, Mass., Jan. 28, 2025 (GLOBE NEWSWIRE) -- Walden Biosciences, Inc. (“Walden”), a private, venture-backed biotechnology company advancing disease-modifying therapies to transform the ...

even in advanced chronic kidney disease; cysts derived from proximal tubules, but not those derived from distal tubules, contained increased concentrations of bioactive erythropoietin.

Researchers at the University of Pennsylvania's Perelman School of Medicine have identified over 1,000 genes that could serve ...

The role of the kidney in blood glucose-level regulation was until recently underestimated. Renal gluconeogenesis, renal glucose uptake and tubular glucose reabsorption are the three ways of renal ...

Nephrotoxicity, the major complication of long-term therapy with amphotericin B, is attributed to drug-induced renal vasoconstriction plus a direct toxic action on renal tubules. Hypokalemia and ...

FIGURE 2. Overview of kidney cell types. Abbreviations: PCT, proximal convoluted tubule; PST, Proximal straight tubule; DTL, descending thin limb of loop of Henle; ATL, ascending thin limb of loop of ...