Although the gene has been studied in other physiological and pathological contexts, its role in kidney disease had not been experimentally tested. In the study, "PPDPF preserves integrity of proximal ...

Transform your drug development pipeline with Newcells’ Renal Proximal Tubule Cells Model eBook. This eBook provides insight into the science behind aProximate ™, an innovative proximal tubule ...

The kidney is a central organ of the mammalian ... promoting differentiation into proximal tubules. Finally, The most proximal part develops into glomeruli under the control of genes such as ...

Researchers at University of Tsukuba have found that the phosphate concentration in proximal tubule fluid, estimated from urine and blood tests, is associated with elevated renal tubular damage ...

An alternative approach, to which we subscribe, involves finding a limited number of biomarkers that identify injury to primary sites in the kidney, such as the glomerulus or the proximal tubule ...

even in advanced chronic kidney disease; cysts derived from proximal tubules, but not those derived from distal tubules, contained increased concentrations of bioactive erythropoietin.

Thus, the two types of kidney - opisthonephric and metanephric ... In reptiles, birds and mammals, the metanephric tubules become differentiated into three regions: proximal, intermediate and distal.

characterized by impaired reabsorption of cystine and dibasic amino acids in the renal proximal tubules. It exhibits a sex-dependent response, with males experiencing an earlier onset of stone ...