Furthermore, the emerging idea that glial cells can act as multipotent progenitors seems to be true not only in the CNS, but also in the PNS, as SCPs, like radial glia, can give rise to unexpected ...

Our results indicate that aberrant midline crossing by motor neuron cell bodies and axons in mice lacking Robo1 and Robo2 are not interdependent and that DCC contributes to axon, but not cell body ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Benraiss and Goldman also demonstrated that the same agents could induce new medium spiny neuron formation ... cell replacement therapies. Research in Goldman’s lab has shown that glial cells ...

The cerebral cortex, which is responsible for higher cognitive functions, relies on the coordinated asymmetric division cycles of polarized radial glial progenitor cells for proper development.

In the mouse brain, Arx is expressed not only in the olfactory bulb (OB) and cerebral cortex progenitor cells but also in these gamma-aminobutyric acid (GABA)-releasing interneurons. In the initial ...

Cartilage and bone development: Three paths to skeleton formation Date: March 27, 2025 Source: University of Basel Summary: In vertebrates, the skeleton of different regions of the body arises ...

those cells may then need a secondary inflammatory process to drive tumor formation. Knowledge about what pushes tumors to develop could be used for comprehensive personalized risk assessment ...

These domains promote interactions with neuronal proteins such as fibronectin leucine-rich repeat transmembrane proteins, promoting adequate synapse formation ... substrates of meprin β. HEK 293T ...