From a tiny sample of tissue no larger than a grain of sand, scientists have come within reach of a goal once thought unattainable: building a complete functional wiring diagram of a portion of the ...

Vision is one of the most crucial human senses, yet more than 300 million people worldwide are at risk of vision loss due to ...

Schematic diagram of the mechanism of retinal regeneration through ... to the eyes of RP1 retinitis pigmentosa model mice ...

The retina is an extremely complex structure that acts as a biological "transducer" of light into neural signals. It is here, in the layer of photoreceptors—cones and rods—that the process of ...

gmail.com; Professor Clement C Tham; clemtham{at}cuhk.edu.hk Purpose To compare the rates of peripapillary vessel density (pVD) loss and retinal nerve fibre layer (RNFL) thinning in normal tension ...

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

This study by Lum and colleagues reports on the role of Afadin, a cytosolic adapter protein that organizes multiple cell adhesion molecule families, in the generation and maintenance of complex ...

To improve the quality control of organoids, we introduced a live imaging technique based on two-photon microscopy to non-invasively monitor and characterize retinal organoids ... and laminated ...