Our laboratory studies both stem cell-intrinsic and extrinsic mechanisms altering tissue renewal capacity, and how such mechanisms ultimately result in the functional decline we recognize as aging.

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

and protected populations of T cells with short telomeres from early aging, the team found. There was also an increase in the number of stem-like memory T cells, which are able to perform either ...

"With aging, neural stem cells don't respond the way they used to when they were young," says Rebecca Kuntz Willits, Northeastern professor of chemical and bioengineering. "There's fewer of them ...

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

Two independent clinical trials demonstrate the safety of stem cell therapies for Parkinson's disease. The papers, published ...

He explained that the skin is the largest organ and undergoes both chronological and extrinsic ... of skin aging such as ...

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, ...

His parents enrolled him in a study that was collecting and storing immature testicular tissue, and the sperm-forming stem cells in them ... the processes behind aging, discusses the surprising ...

As we age, our skin undergoes two types of aging: intrinsic aging, which happens naturally over time, and extrinsic aging ...

The Silberstein lab initially became interested in Sema4A while looking for extrinsic, so called “niche” factors ... functional identity of myeloid-biased hematopoietic stem cells. Nature Aging. DOI: ...

However, as we age, capacity of stem cells declines, and the resulting drop in tissue repair manifests as the functional decline associated with aging. Our goal is to understand why stem cell activity ...