While a genetics company saw success with a dire wolf revival, can it pull off the Colossal feat of de-extinction in other ...

Using dire wolf DNA extracted from fossils – yes, dire wolves aren't just the stuff of "Game of Thrones" fiction, they ...

Colossal Biosciences bold announcements about its project to replicate dire wolf traits have drawn criticism from many ...

Wolfdogs are becoming a popular choice worldwide with people looking for furry companions. Conservationists are growing ...

“Ancient DNA is more like confetti,” she says. Most of the dire wolf DNA snippets the team recovered were about 35 letters long.

Colossal’s scientists then took cells from a gray wolf—with whom the dire wolf shares 99.5 percent of its DNA—and used CRISPR to edit the genes to be more like a dire wolf.

The dire wolf's closest living relative A 2021 study in the journal Nature that included several co-authors associated with Colossal compared DNA from dire wolf fossils with DNA from seven living ...

Colossal Biosciences is pursuing this plan, having already revived the dire wolf using grey wolf DNA, and is working on projects to bring back the giant moa bird and other extinct animals. In the ...

The fossil tooth from Ohio used for the DNA extraction is around 13,000 years old. According to USA TODAY, Colossal harvested ancient DNA from real dire wolf fossils to create dire wolf genomes.

The company decided on the gray wolf since it appeared closely related to the dire wolf, with the two species sharing 99.5% of its DNA, Colossal said in a press release.

After extracting the DNA from the dire wolf fossils (one of which was more than 72,000 years old) and analyzing it, the company took a sample of blood vessel cells from gray wolves and used gene ...