Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...
The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, ...
A study published in Nature looks at a genetically modified pig-to-human liver xenotransplantation. Prof Peter Friend, Professor of Transplantation, University of Oxford, said: ...
Expression data from patient-derived xenograft (PDX) mouse models exposed to micvotabart pelidotin (MICVO) indicate gene signatures associated ...
Novel trispecific T cell engager, ZW209, demonstrates potent preclinical efficacy against DLL3-expressing tumors and an encouraging safety ...
Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK ...
In this study, CAR-T cells were engineered to secrete both IL-15 and CCL19, and their efficacy was evaluated in a human glioblastoma orthotopic xenograft model. The results reveal that 15 × 19 CAR-T ...
Center for Cancer Diagnosis and Treatment, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province 215000, China ...
Get Instant Summarized Text (Gist) CRISPR technology was used to eliminate 50% of head and neck tumors in animal models by targeting the SOX2 gene, essential for cancer cell survival. The method ...
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