At least two people were killed Friday after a small airplane crashed onto a busy road and collided with a bus in São Paulo, southern Brazil, injuring several others. The crash took place around 7:20 a.m. local time (5:20 a.m. ET) along Avenida Marquês in the coastal district of Barra Funda, CNN affiliate CNN Brasil reported.

Tragedy struck in São Paulo as a small plane crashed into a bus on the bustling Marques de São Vicente Avenue, leaving two people dead and two others injured. Emergency services confirmed the fatalities were aboard the plane,