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Remarkably, mutant centrioles also have an expanded proximal region. During mitosis, these mutant centrioles further elongate before fragmenting and disintegrating. All four proteins physically ...

Without triplet microtubules centriolar cylinders can still form, but are unstable, resulting is futile rounds of de novo centriole assembly during S phase and disassembly during mitosis. Here the ...

In particular, we address the alternating, dual role of the mother centriole (i) as a component of one of the spindle poles during mitosis, and (ii) as the basal body of the primary cilium in ...

This study shows that the de novo formed centrioles in the early developing mouse gradually mature to participate in mitosis and cilia formation around gastrulation, when the mitotic surveillance ...

In this review, we have highlighted the latest findings regarding the role of Astrin in KT-MT attachment during mitosis, and summarized the functions in centriole duplication and centrosome integrity.

For mitosis to occur, the chromosomes in each pair must be pulled apart to opposite poles of the dividing cell. This action centers around the small cell organelles called centrioles which are ...

Scientists now examine how centrioles contribute to this process. The findings help to elucidate the function of these tiny cellular structures in mitosis. Mitosis is the process by which the ...

Mitosis allows for cells to produce identical ... emerges from two structures called the centrioles, positioned at either end of the cell. The meiotic spindle latches onto the fused sister chromatids.

Mitosis is the process by which a cell segregates ... The mitotic spindle, a network of protein filaments, emerges from structures called centrioles, positioned at either end of the cell.

Microtubules are the principal structures making up the centrioles. The centrioles in turn are the principal agents in cell duplication and division (mitosis). The microtubules are seen to be long ...