We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

Background The gold standard of paediatric obstructive sleep apnoea syndrome (OSAS) diagnosis is overnight polysomnography (PSG). Validated screening methods for paediatric OSAS are limited.

Nirsevimab, a long-acting monoclonal antibody, was introduced last season (2023–2024) in some countries with the aim of reducing the burden of disease caused by respiratory syncytial virus (RSV) in ...

The relief of pain and anxiety associated with painful or invasive procedures is a top priority in paediatrics. A ‘Sounding Board’ in the New England Journal of Medicine 30 years ago stated that ‘The ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant expression of 15q11.2-q13 imprinted genes. Due to their rarity, data on ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Population and data. The CHiCS cohort and study design have been described in detail previously.18 The cohort includes 13 830 children and young people who were in care between August 2009 and July ...

Objective It is important to detect reduced peripheral perfusion due to hypovolaemia early before it progresses to shock. Capillary refill time (CRT) and manual palpation for peripheral coolness are ...

Objective Body mass index (BMI), and its adjustment for age and sex as a z-score, is a common measure of excess weight but performs poorly in children. Waist circumference to height ratio (WHtR), ...

Objective Neonatal sepsis is a significant cause of morbidity and mortality, particularly in preterm infants. Despite its routine use in adults, the diagnostic utility of complete blood count (CBC) in ...